RESUMO
No disponible
Assuntos
Humanos , Masculino , Idoso , Leishmaniose Cutânea/diagnóstico , Meglumina/uso terapêutico , Crioterapia , Leishmaniose Cutânea/tratamento farmacológico , Leishmania/patogenicidadeRESUMO
No disponible
Assuntos
Humanos , Masculino , Idoso de 80 Anos ou mais , Leucemia Mielomonocítica Aguda/diagnóstico , Eritema/etiologia , BiópsiaRESUMO
No disponible
No disponible
Assuntos
Adulto , Humanos , Micose Fungoide/diagnóstico , Neoplasias Cutâneas/diagnóstico , Micose Fungoide/patologia , Neoplasias Cutâneas/patologia , Dorso/patologia , BiópsiaRESUMO
Mujer latinoamericana de 50 años que acudió a la consulta por lesiones pruriginosas de reciente aparición en los brazos y muslos. En la exploración observamos múltiples pápulas planas en las extremidades, así como máculas hipopigmentadas en el tronco que, según refería la paciente, comenzaron a aparecer en la infancia. Se realizó el estudio histológico de ambos tipos de lesiones en el que se apreciaron en las capas altas de la epidermis unos queratinocitos aumentados de tamaño con citoplasma de color azul pálido. Se han descrito más de 20 tipos de virus del papiloma humano (VPH) asociados a epidermodisplasia verruciforme (EV) (VPH-EV). Aunque antes se pensaba que estos eran específicos de la EV, gracias a nuevas técnicas de biología molecular, se han aislado secuencias de VPH-EV en enfermedades cutáneas con hiperproliferación epidérmica tanto benignas como malignas en población inmunocompetente
We present the case of a 50-year-old Latin American woman who consulted her physician because of recent pruritic lesions on her arms and thighs. During the examination, we observed multiple flat papules on the limbs, as well as hypopigmented macules on the trunk which, according to the patient, began to appear during childhood. A histological study was performed on both types of lesions, and showed some enlarged keratinocytes with light blue cytoplasm in the upper layers of the epidermis. More than 20 types of HPV associated with EV (HPV-EV) have been described. Although it was previously thought that these were specific to EV, new molecular biology techniques have made it possible to isolate HPV-EV sequences in skin diseases, both benign and malignant, with epidermal hyperproliferation in the immunocompetent population
Assuntos
Feminino , Pessoa de Meia-Idade , Humanos , Epidermodisplasia Verruciforme/diagnóstico , Epidermodisplasia Verruciforme/terapia , Queratinócitos/citologia , Queratinócitos/patologia , Papillomaviridae/patogenicidade , Epidermodisplasia Verruciforme/complicações , Queratinócitos , Papiloma/complicações , Papiloma/diagnóstico , Verrugas/complicações , Verrugas/diagnóstico , Epidermodisplasia Verruciforme/etiologia , Epidermodisplasia Verruciforme/patologiaRESUMO
We present the case of a 50-year-old Latin American woman who consulted her physician because of recent pruritic lesions on her arms and thighs. During the examination, we observed multiple flat papules on the limbs, as well as hypopigmented macules on the trunk which, according to the patient, began to appear during childhood. A histological study was performed on both types of lesions, and showed some enlarged keratinocytes with light blue cytoplasm in the upper layers of the epidermis. More than 20 types of HPV associated with EV (HPV-EV) have been described. Although it was previously thought that these were specific to EV, new molecular biology techniques have made it possible to isolate HPV-EV sequences in skin diseases, both benign and malignant, with epidermal hyperproliferation in the immunocompetent population.
